☆ 1.指南编写委员会 ☆

    指南编写委员会（Guideline Writing Committee，GWC）的成员由ESVS选出，包括血管外科医生、血管内科医生、介入放射科医生和妇产科医生等代表参与CVD治疗的临床医生。正如介绍性会议所商定，所有委员会成员都参与了各自负责章节和段落的证据选择和评级工作（参见附录主题、检索词和责任作者的补充表）。GWC的所有成员都参与了最后推荐意见的制定。

    委员会成员提供了所有可能被视为确实的或潜在利益冲突来源关系的披露声明。这些文件已归档，可在ESVS总部获得。成员在制定指南过程中，没有得到任何制药、器械或外科行业的资金支持。

☆2.指南制定工作流程☆

         GWC于2019年11月在荷兰阿姆斯特丹举行了一次介绍性会议，会上确定了主题和作者任务清单。委员会成员的意见由主席和联合主席汇编成指南草案。在完成初稿并经过内部审查后，委员会于2020年9月在德国法兰克福再次召开会议审查并核准了每项建议的措辞。指南随后经历了三轮外部审查，并进行了适当的修订。

☆ 1. Guideline Writing Committee. ☆ 

       Members of the Guideline Writing Committee (GWC) were selected by the ESVS to represent clinicians involved in the treatment of CVD and included vascular surgeons, vascular physicians, an interven tional radiologist, and a gynaecologist-obstetrician. All members of the GWC were involved in selecting and rating the evidence for each of the different chapters and subsections under their responsibility (see Appendix with Supplementary Table of topics, search terms, and responsible authors), as agreed in the introductory meeting. All GWC members were involved in formulating the final recommendations.

       GWC members have provided disclosure statements regarding all relationships that might be perceived as real or potential sources of conflicts of interest. These are filed and available at the ESVS headquarters. GWC members received no financial support from any pharmaceutical, device, or surgical industry to develop these guidelines.

☆2. Workflow for producing the guidelines.☆

       The GWC held an introductory meeting in November 2019 in Amsterdam, Netherlands, at which the list of topics and author tasks were determined. Contributions from GWC members were compiled into a draft of the guidelines by the chair and co-chair. After the first draft was completed and internally reviewed, the GWC met again in September 2020 in Frankfurt, Germany, to review and approve the wording of each recommendation. The guidelines then underwent three rounds of external reviews, and appropriate revisions were implemented.

☆ 3. Literature search. ☆

       GWC members agreed on a common sys tematic literature search strategy for each of the chapters. A comprehensive literature search of articles published was performed using MEDLINE (through PubMed), Embase, Car diosource Clinical Trials Database, and the Cochrane Library databases between 1 January 2013 and 30 June 2020, for relevant papers published in English.The search terms used for the different chapters and subsections are mentioned in the Appendix (Supplementary Table). Reference checking and manual search by the GWC members added other relevant literature. Only peer reviewed, published literature and studies presenting pre-defined outcomes were considered. The selection process followed the “pyramid of evidence”, with aggregated evidence at the top of the pyramid (meta analyses of several randomised controlled trials [RCTs], other meta-analyses, and systematic reviews), followed by RCTs and finally observational studies. Single case reports, abstracts, and in vitro studies were excluded, leaving expert opinion at the bottom of the pyramid. Articles published after the search date or in another language were included only if they were of paramount importance to this guideline. After the first and second external review, the members of the GWC performed a second and third literature search within their area of responsibility to determine if any important publications had been published between July 2020 and February 2021, and further until the end of June 2021, respectively.